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KMID : 0357919830170040477
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Korean Journal of Pathology
1983 Volume.17 No. 4 p.477 ~ p.480
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A Malignant Schwannoma in von Recklinghausen's Disease
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Abstract
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A case of malignant schwannoma arising from the brachial plexus in von
Recklinghausen's disease was present.
Because of its difficult microscopic recognition, the diagnosis of malignant
schwannoma should be the primary consideration in only two following ciacumstances:
1) when the tumor develops in a patient with von Recklinghausen's disease and 2)
when the tumor is obviously arising within the anatomic compartment of major nerve or
in continuity with an unquestionable neurofibroma.
The authors experienced a malignant schwannoma in a 23-year-old male patient with
von Recklinghausen's disease. The tumor, measuring 17×8×8㎝ in dimension and 500
gm in weight, was arising in continuity with the brachial plexus. Microscopically it
consisted of relatively monomorphic spindle cells with frequent mitoses. A discussion on
the histogenesis and the clinicopathologic characteristics, with a brief literature review,
were described.
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